Wednesday, May 13
Session: Redefining Gene Delivery Through Plant-Based Manufacturing (sponsored by Qiagen)
Description: Cirsium presented in-process AAV characterization data in collaboration with Qiagen, showing how dPCR enables accurate genome titer quantification from crude plant lysate and go/no-go batch decisions in under three hours.
Thursday, May 14
Abstract #269: Detailed characterization and quantification of post-translational modifications on AAV capsids produced in whole tobacco plants using peptide mapping and LC-MS/MS
Description: Cirsium presented LC-MS/MS peptide mapping data comparing PTMs on plant-produced AAV9 and AAV2 capsids to HEK293 reference material.
Friday, May 15
Fireside Chat: Engaging with ARPA-H: Funding Priorities And Future Directions
Description: Cirsium’s CEO, Dan Gibbs, joined Daria Fedyukina, PhD from ARPA-H and, ASGCT President, Terence Flotte to discuss agency funding priorities, how to engage with ARPA-H programs, and emerging regulatory signals shaping the future of cell and gene therapy.