Planting
seeds of
innovation

Democratizing gene therapy through transformative manufacturing methods

Eliminating current
manufacturing
bottlenecks

Number 1 icon
Lack Of Adequate Production Capacity Globally
Icon for global scale challenges in gene therapy manufacturing industry
Number 2 icon
Poor
Scalability
Icon for scaling challenges in gene therapy manufacturing industry
Number 3 icon
High Cost Of Clinical Grade Manufacturing
Icon for high cost challenges in gene therapy manufacturing industry
Number 4 icon
Standardization Of Clinical Grade Production Methods
Icon for production method challenges in gene therapy manufacturing industry
Icon for global scale challenges in gene therapy manufacturing industry
Number 1 icon
Lack Of Adequate Production Capacity Globally
Icon for scaling challenges in gene therapy manufacturing industry
Number 2 icon
Poor
Scalability
Icon for high cost challenges in gene therapy manufacturing industry
Number 3 icon
High Cost Of Clinical Grade Manufacturing
Icon for production method challenges in gene therapy manufacturing industry
Number 4 icon
Standardization Of Clinical Grade Production Methods

OUR PLATFORM REMOVES THESE LIMITATIONS

OUR BIOREACTORS
ARE PLANTS

We develop viral vector production methods and systems using whole plants as bioreactors.

Cirsium Biosciences gene therapy manufacturing benefits for scaling producation methods using plants

Highly-Scalable

By using plants as production base unit, our platform uses a linear scale out production model.

This enables swift and reproducible scaling, without the need for significant process development, unlike traditional AAV production.

Cirsium Biosciences gene therapy manufacturing benefits for rapid production time using plants in gene manufacturing

Rapid

Our platform significantly expedites process development through the synergy of modular plant production technology, plant reproducibility, and immediate production capacity access, eliminating high-purity plasmid delays.

Our process achieves up to 70% reduction in manufacturing lead times for vital gene therapies, offering patients expedited access and life-saving opportunities.

Cirsium Biosciences benefits for cost effectiveness using plants in gene manufacturing

Cost-Effective

Utilizing a non-GMP upstream controlled environment agriculture (CEA) space, our platform produces up to 1e15vg/kg of recombinant AAV vector.

This brings significant cost reductions when compared to traditional cGMP facilities.

Cirsium Biosciences gene therapy manufacturing benefits for safety production methods using plants

Safe & Simple

Our platform simplifies the supply chain and reduces batch failures using a human pathogen resistant platform.

Get in touch

For general questions, investment possibilities, or scientific queries, please contact us. To learn more about a career with us, explore our career opportunities.