Planting the Future of Gene Therapy

Harnessing the Manufacturing Power of Biopharming

our platform

With cutting-edge production technology, we utilize transient gene delivery in plants and high-density Controlled Environment Agriculture (CEA) to manufacture high-quality AAV vectors for genetic medicine.

TRANSFORMATION
INFILTRATION
EXTRACTION
First step of Cirsium Biosciences gene therapy manufacturing platform process Plant-specific Helper Plasmids icon
Plant-Specific Helper Plasmids
Second step of Cirsium Biosciences gene therapy manufacturing platform with delivery vector icon
Delivery Vector
Third step of AAV gene manufacturing Cirsium Biosciences platform with processor plants
Producer Plants
Fourth step of Cirsium Biosciences gene therapy manufacturing platform process to AAV Vector Production & Purification icon
AAV Vector Production & Purification
First step of Cirsium Biosciences gene therapy manufacturing platform process Plant-specific Helper Plasmids icon
Plant-Specific Helper Plasmids
TRANSFORMATION
Second step of Cirsium Biosciences gene therapy manufacturing platform with delivery vector icon
Delivery Vector
INFILTRATION
Third step of Cirsium Biosciences platform with processor plants
Producer Plants
Upstream
Downstream
EXTRACTION
Fourth step of Cirsium Biosciences gene therapy manufacturing platform process to AAV Vector Production & Purification icon
AAV Vector Production & Purification

Upstream Non-GMP

Downstream GMP

OUR PROCESS

Our industrialized, scalable process significantly outpaces competitors, delivering unmatched speed and cost-effectiveness in AAV vector manufacturing.

AAV CONSTRUCT
DESIGN & VALIDATION

INFILTRATION

CLARIFICATION
& PURIFICATION

4 – 6 WEEKS

< 1 WEEK

~ 1 WEEK

~ 1 WEEK

AAV
ASSEMBLY
PROCESS
COMPLETION
AAV CONSTRUST DESIGN & VALIDATION
4 - 6 WEEKS
AGRO-INFILTRATION
< 1 WEEK
AAV ASSEMBLY
~ 1 WEEK
CLARIFICATION & PURIFICATION
~ 1 WEEK
PROCESS COMPLETE

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