Senior
Research
Associate I

Cirsium Biosciences is creating the next generation of manufacturing technologies for viral vector production. Our novel plant-based platform solves the existing problems of speed, ﬂexibility, scalability, and safety in viral vector manufacturing while dramatically reducing production costs. Our goal is to enable global and equitable access to life-changing genetic therapies.

Position Overview

We are seeking a highly skilled and motivated Senior Research Associate I to join our dynamic team. The successful candidate will play a critical role in our molecular biology research projects, with a focus on cell culture, and other in vitro assays. This individual will collaborate closely with cross-functional teams to generate high-quality data and provide insights into compound activity, mechanism of action, and biomarker identification. The ideal candidate will be ready to start immediately and contribute to our innovative research initiatives.

Key responsibilities

Maintain and culture mammalian cell lines, primary cells, and co-culture systems.
Conduct screening and pharmacological profiling of drug candidates.
Utilize molecular and biochemical techniques such as, RNA isolation, RT-qPCR, Western blotting, ELISA, and immunofluorescence.
Develop and perform in vitro cellular assays, including cell viability, proliferation, apoptosis, and mechanistic studies.
Analyze experimental data, ensure reproducibility, and present findings to cross-functional teams.
Work collaboratively with other teams to support assay development, data interpretation, and project advancement.
Maintain detailed and organized records, write technical reports, and contribute to regulatory documentation.
Stay updated with advancements in assay technologies and cell-based model development.
Provide technical guidance and mentorship to junior team members as needed.

Qualifications

M.S. in Biology, Molecular Biology, Cell Biology, or a related field with 2-5 years of relevant laboratory experience, or a B.S. with 5-7+ years of hands-on research experience.
Strong expertise in in vitro assay development, optimization, and execution.
Proficiency in mammalian cell culture techniques, including working with primary cells and 3D culture models.
Familiarity with gene modulation techniques (e.g., CRISPR, siRNA/shRNA) is a plus.
Experience with data analysis software such as GraphPad Prism, FlowJo, or ImageJ.
Strong organizational and time-management skills with the ability to handle multiple projects.
Excellent communication skills and ability to work in a collaborative, fast-paced environment.

CIRSIUM EMPLOYEE BENEFITS

Cirsium Employee Benefits

Competitive Salary

Stock Options

24 Paid Time Off Days & 13 Paid Holidays

Professional Development Opportunities

Health Insurance & Health Savings Account

401(k) Plan

Dental Insurance

Life & AD&D Insurance

Vision Insurance

Employee Assistance Program (EAP)

And More...

Cirsium Biosciences is an emerging company located in San Diego, California. We offer highly competitive compensation and employee programs, including comprehensive health, dental and vision plans, generous time off, and equity in our early-stage company. We are dedicated to fostering a workplace that keeps our team inspired and engaged. We offer an inclusive company culture where employees feel respected and valued.

Cirsium Biosciences is proud to be an equal opportunity employer. All qualiﬁed applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, national origin, genetics, disability, age, sexual orientation, veteran status, or any other protected categories.

PLEASE EMAIL YOUR RESUME TO CAREERS@CIRSIUMBIO.COM TO APPLY.

SeniorResearchAssociate I

Position Overview

Key responsibilities

Qualifications

CIRSIUM EMPLOYEE BENEFITS